Based on a series of wind tunnel tests conducted on the rigid model of an actual high-rise building, wind dynamic interference effects on the target building of the proposed super high-rise building and other surrounding buildings were investigated. The results show that upon completion of the proposed building upstream, the shielding effect of it will generally reduce the along-wind mean aerodynamic force of the existing buildings downstream. However, the vortex shedding in its wake may lead to a significant increase in the acrosswind peak wind load of the existing buildings downstream, which means that these downstream buildings under the original structural design may no longer be safe.