| In this paper, based on finite element software Abaqus, a three-dimensional adaptive integrated modeling and simulation algorithm is established for the mirror assembly process of a conical nested Wolter-I X-ray focusing telescope. First, using Python language combined with Abaqus script interface for secondary development, an adaptive modeling simulation algorithm is proposed, and the stress distribution and surface deviation distribution of the mirror under different working conditions is accurately obtained. Then, the graphical user interface (GUI) is developed to build a more operability plug-in, which greatly improves the simulation efficiency and accuracy, and saves experimental and labor costs. The results give the ideal mirror thickness and optimal assembly load. Finally, a more reasonable evaluation method of surface deviation is obtained, which provides an important theoretical basis for optical path analysis and guidance for the actual assembly process.