In this paper,the seismic response of a three-span fault-crossing continuous girder bridge subjected to near-fault pulse-like seismic ground motions is calculated considering the fling-step effect. Typical near-fault pulse-like ground motion records are selected and nonlinear response history analyses are adopted in an asynchronous excitation scenario. The effect of cable restrainers on the seismic response of fault-crossing bridges is investigated under different fault locations. In addition, parametric analyses on lateral restraining displacement and lateral stiffness of the cable restrainer are conducted. Results show that using the cable restrainer can effectively mitigate the displacement response of fault-crossing bridges while it enlarges the pier-bottom moment; seismic responses of a fault-crossing bridge are more sensitive to changes in the lateral restraining displacements of the cable restrainer.